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The advantage of studying the three different hematological malignancies together was to contrast between malignancy types needing intensive treatment upfront (AML) and those with slower tumor progression in need of more intermediate-intensity treatment (myeloma, CML).
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Therefore, uniform disease mechanisms pertinent for disease progression in T2D need to be identified.
CLL shows a heterogeneous clinical course, with many patients having an indolent disease while others suffering from rapid disease progression and are in need of early treatment [ 1].
These findings indicate that in non-muscle-invasive bladder cancer, assessment of PODXL could be of potential clinical value for monitoring of tumours with high risk of progression and, hence, patients in need of more aggressive first-line therapy or primary cystectomy.
A new biomarker for predicting radiographic progression in RA is needed.
Identification of novel macrophage mediators that can regulate polarization and thus influence development and progression in ALD is needed.
However, the identity of the factors that may participate with Pygo2 to regulate cell cycle progression in lung cancer needs to be further explored.
To avoid the postdoc trap, young scientists need to be aware of the state of their career progression in academia, and they need to keep an open mind to the myriad of other sectors where they can also apply their skills and find highly rewarding careers.
In addition to confirming that duration of diabetes, high levels of glycaemia and high blood pressure are risk factors for progression of diabetic retinopathy, the present study found that large changes in glycaemia and systolic blood pressure were independent risk factors for progression to diabetic macular oedema in need of photocoagulation treatment.
Besides making higher education accessible for low-income students, this program serves as an incentive for people who wish to go into public service by offering targeted loan cancellations for specific progression in areas of national need including teaching, nursing and law enforcement.
Thus, in order to decrease CNS progression in melanoma patients, we need drugs with a greater systemic activity, able to cross the BBB and active in the CNS growing metastatic cells (Gerstner and Fine, 2007).
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