Sentence examples for progression implies that from inspiring English sources

10 11 The short survival time after progression implies that differences in OS are likely to be observed for truly effective new treatments.

Progression implies that an individual is initially diagnosed with an early stage of the disease with worsening at the current examination, while regression implies the presence of the disease at the preceding examination with an improvement at the current examination.

The dissociation between relapses and progression implies that relapses (except possibly during Years 1 and 2) are not a valid outcome surrogate for the late disability constituting the main social, medical and economic impact of multiple sclerosis.

The cancer stem cell model of tumour development and progression implies that tumours contain a subset of cells that can both self-renew and give rise to a differentiated progeny (Eaves, 2008).

The substantially higher expression levels of EPHA2 on OS compared with healthy bone, in addition to its role in cancer progression, implies that EPHA2 could be a suitable therapeutic target itself and this has been the topic of studies in several malignancies.

Loss of any component of the mammalian TREX2 complex elicited a defect either in mRNA export or in the regulation of cell cycle progression, implying that each TREX2 component has an important individual function.

On the other hand, combined therapies did not definitely prevent disease progression, implying that some aspects of the complex GLD pathology might be more refractory to correction than others, with important implications for potential clinical translation.

Angiogenesis, the formation of new blood vessels from pre-existing vasculature, is crucial for tumour growth and cancer progression, implying that anti-angiogenic drugs are likely to be of importance in the treatment of neoplasia (Weidner et al., 1991; Bergers and Benjamin, 2003).

A recent systematic literature review of 57 clinical studies also found that time-integrated measure of disease activity indicators positively correlated with radiographic progression which implies that monitoring of dynamic disease activity indicators might be more valuable in predicting radiographic progression [ 29].

These data suggest down-regulation of XAF1 expression to be implicated in ccRCC progression and implies that its re-induction may provide a therapeutic approach.

The "asymmetrical serial progression" model implies that the specification into the cortical lineage is the default pathway downstream of the TEC bipotent progenitors.