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The union was also dismayed to find that prison educators did not feature in the review: with little access to continuing professional development, no obvious career progression, high stress levels and, where they work for multiple contract holders, isolation from management, it says it's no wonder morale is low.
Walking around Sol LeWitt's mysterious concrete ziggurat — titled "Irregular Progression High No. 7," and on loan from the Pace Gallery — she paused to appreciate the carpet of evergreen needles that surrounded it.
The letter adds: "It is absolutely in the national interest that MPs have the staffing capacity to handle this and support them at this critical time". The signatories complain they face "extremely limited staff progression, high staff turnover and low morale".
Although diabetes is associated with a marked accumulation of vascular smooth muscle cells (VSMC) in fibroatheromas, representing an integral part of atherosclerotic lesion progression, high glucose and insulin levels do not directly induce VSMC proliferation and accumulation in vivo [1].
Consistent with their role in tumor progression, high levels of several MMP family members have been shown to correlate with poor prognosis [ 11, 12].
Consistent with their role in tumor progression, high levels of a number of MMPs have been shown to correlate with poor prognosis in human cancers [ 9- 11].
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Mattey et al., demonstrated in 1999 [16], that GSTM1 null RA patients had more severe radiological progression (higher Larsen score) independent of the effect of the HLA-DRB1 associated shared epitope (SE).
Most of these tumors were "high-risk" (stage T1 or grade 3); however, we included 4 primary stage Ta grade 2 tumors with later progression ("high-risk in retrospect") (Table 1).
Patients with chemotherapy response were evaluated by a Thoracic Surgeon (JFC-C) to determine whether they were candidates for surgical treatment after four cycles of chemotherapy; if surgery was not possible, chemotherapy continued up to six cycles until disease progression, high-grade toxicity, or withdrawal of informed consent.
This type of breast cancer is associated with an aggressive disease progression, higher histological grade, poor prognosis, high rate of recurrence and decreased survival rates.
A later study observed that combining Herceptin with doxorubicin plus cyclophosphamide produced longer time to progression, higher response rates and improved survival rather, as opposed to simple chemotherapy.
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