Sentence examples for progression from primary from inspiring English sources

Integrins are the main cellular adhesion receptors that through multifaceted roles as signalling molecules, mechanotransducers and key components of the cell migration machinery are implicated in nearly every step of cancer progression from primary tumour development to metastasis.

Focusing on invasive ductal breast cancer (IDC), we have found dysregulated expression in tumor samples of several microRNAs, including the miR-200 family, along progression from primary tumors to distant metastases, further reflected in higher blood levels of miR-200b and miR-7 in IDC patients with regional or distant metastases relative to patients with primary node-negative tumors.

The level of p53 was gradually reduced upon progression from primary keratinocytes, through early to late HF1 cells (Figure 3A).

In this study we are not able to distinguish between cavitory tuberculosis caused by progression from primary infection, re-infection, or indeed by canonical post-primary reactivation disease.

Expression is also downregulated in 50% of cases during progression from primary carcinoma to metastatic lesions.

Yet, mechanisms of progression from primary tumor to oligometastasis, rather than to polymetastases, is lacking in detail.

Analytical and numerical results show an interesting relationship between the rates of progression, from the primary and secondary stages of infection, the treatment rates, for individuals in the primary and secondary stages, and the reproduction number and incidence of syphilis in the population.

There is really no reliable method for recapitulating the metastatic progression from a primary tumor in the colon to the liver," says Omer Yilmaz, an MIT assistant professor of biology, a member of MIT's Koch Institute for Integrative Cancer Research, and the lead senior author of the study, which appears in the May 1 issue of Nature Biotechnology.

We, on the other hand, noticed a marked reduction in the motility of cells during the progression from the primary keratinocytes and early HF1 to late HF1 cells.

Patient self-management is a logical progression from the primary care model.

Numbers of suppressor/regulatory T lymphocytes, as measured by FOXp3, almost double with progression from skin primary to negative SLN, and there are similar increases in IL-10.