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Most of the studies concerning the roles of GPCs in breast cancer progression focus on the role of the GPC3 member.
In this review, we present the deregulated pathways involved in GBM formation and progression, focus on the mechanisms underlying TMZ resistance in GBMs and discuss metabolomics-based approaches that could be leveraged in the quest to improve the current therapeutic outcomes in GBMs.
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Using microarray technology, we analyzed MM and normal pleural samples identifying new genes involved in tumour progression, focusing our attention on the identification of putative biomarkers for early diagnosis and prognosis in MM.
Other studies have looked into the role that EMPs play in MS progression, focusing on specific disease mechanism [ 152, 170].
Here, we discuss the role of PARs and their activators in cancer progression, focusing on TF- and thrombin-mediated actions.
This review outlines the reports that establish the impact of MAPK pathways on tumor progression, focusing not only on malignant cells but also on the host environment, including stromal cells.
This review aims to highlight some of the regulatory pathways involved during the HIV-1 infection and disease progression, focusing on the novel discovered microRNAs (miRNAs) and their relation with immune system's agents.
The striking correlations between changes in Fau and MELK expression and breast cancer progression focused attention on their common target, Bcl-G, in order to determine whether Bcl-G expression levels, or the post-translational modifications by Fau and MELK, were more important in controlling its activity.
This is where I pulled back from focusing on melodic progression to focus more on the abstract elements.
More recently, particular emphasis has been placed upon those features of cancer progression that focus on cancer as a participant in localized microenvironments that it partially creates [4, 5].
Since we used CD34+ cells from 3 different tissues with distinct engraftment potential, we were able to subtract genes that were differentially expressed merely due to cell cycle progression and focus on engraftment related genes only.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com