Furthermore, it is difficult to compare these outcomes across studies as clinical assessments to determine disease progression are conducted at different frequencies in clinical trials and observational settings; infrequent assessment for disease progression could lead to overestimating PFS.
To confirm that gankyrin overexpression impedes cell cycle progression, we conducted flow cytometric analysis on selected GFP positive cells from GFP-p16ink4a-transfected cells.
To gain insight into the role of genomic alterations in breast cancer progression, we conducted a comprehensive genetic characterization of a series of four cell lines derived from MCF10A.
To further determine the influence of HCV coinfection with HIV-1 on disease progression, we conducted a prospective cohort study and calculated the percentages of individuals whose CD4+ T-cell counts remained >200 cells/µl and retained on the cohort study.
Univariate analysis of neutrophil and platelet recovery, TRM, GVHD and relapse or progression was conducted.
Next, detailed study of kras V12-induced tumor progression was conducted on 100 driver-effector fish maintained in water containing 2 μM mifepristone.
Analysis of the prostate cancer progression study conducted by Tomlins et al. [ 13] revealed that in benign samples both EPHB4 and ITGB8 are expressed at a low level and this increases dramatically and significantly in prostatic intraepithelial neoplasia (PIN) (ITGB8: 9.5 fold, p = 1.24 x 10-4 and EPHB4 2.9 fold, p = 0.001), the precursor for prostate carcinoma [ 14].
To identify common genetic markers involved in AD susceptibility and progression, we first conducted a genome-wide association study in 1034 cases and 1186 controls (the re-matched analyzed set included 733 LOAD cases and 792 controls).
To investigate the relationship between the serologic changes and disease progression, we have conducted a prospective study in a high-incidence area in southern China.
Fowler et al. developed this model with mice lacking RAG-2, enabling molecular studies of the host contribution to MM progression to be conducted in vivo (Fowler et al., 2009).
