Sentence examples for progression because of its from inspiring English sources
Although loss of LKB1 by itself may not be sufficient for RCC initiation, it may be important in progression because of its effects on angiogenesis and invasion as demonstrated here.
Thus, whether LTBP3 contributes to tumor progression because of its signaling role or its architectural role remains to be elucidated.
In particular, MT1-MMP appeared to be the most important factor in HCC progression because of its widespread pattern of expression (Harada et al, 1998).
USP7, also known as Herpes virus associated USP (HAUSP), is critical in cancer progression because of its destabilising effect on the tumour suppressor p53 (Refs 8, 42, 43).
Of particular interest, IGF-1 protein has been most strongly implicated in breast cancer progression because of its mitogenic and anti-apoptotic effect on mammary epithelial cells [ 4].
On the other hand, HSP90 proteins were also implicated to be involved in breast cancer progression because of its overexpression in breast cancer cell lines and association with survival of breast cancer [ 19].
Dyspnea may be considered a potential marker of disease progression in COPD because of its link with lung function, the manner in which it changes over time, its utility in predicting mortality, and its responsiveness to therapy.
However, it cannot be used for continuously monitoring the progression of hepatitis because of its invasiveness and lack of accuracy.
Estrogen has traditionally been implicated in SLE disease progression because of the prevalence of the disease in women; however, its role in cardiovascular risk factors such as hypertension is unclear.
HIV is believed to act as a trigger in the causation or progression of some cancers because of its ability to cause immune depression.
Although many factors have been shown to regulate cardiac hypertrophy, mTORC1 is especially important in the progression of this disease because of its central role in regulating protein synthesis and cell size.
