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A breast carcinoma progression array (CC08-00-001; developed by Cybrdi Inc).
Breast carcinoma progression array (CC08-00-001) developed by Cybrdi Inc. (Frederick, MA, USA) was probed by Cybrdi Inc.
Figure 2 shows representative ChREBP immunostaining in the Cybrdi (CC08-00-005) brearrayrogression array, where staining scores showed a clear trend for increasing with the malignant progression as defined by histopathological diagnosis.
To determine whether the observed reduction in Nuc-Stat5a levels could be attributed to a reduction of total cellular Stat5a protein, we quantified levels of total cellular Stat5a protein by using AQUA within the breast tissue progression array.
Cohort II was a breast cancer progression array of specimens from Thomas Jefferson University (Philadelphia, PA, USA) constructed by cutting edge matrix assembly [ 37], comprising 40 healthy breast tissues and 140 breast carcinoma specimens, including ductal carcinoma in situ, primary invasive ductal carcinomas (grades 1 to 3), and lymph node metastases [ 38].
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In invasive ductal carcinoma, ChREBP correlated significantly with mean 'downregulated' hypoxia scores (r=0.3, P<0.015, n=67) and in two distinct breast progression arrays, ChREBP protein also increased with malignant progression (P<0.001).
To reveal a possible link between ChREBP protein and the histopathology of malignant progression, we used two commercially available breast progression arrays that provided us with samples from two independent series of breast cancer cases.
To identify genes involved in gastric cancer progression, lncRNA array analysis was performed on total RNA isolated from three gastric cancer samples, and matched peri-cancerous samples.
Material I was a breast cancer progression tissue array constructed by using cutting-edge matrix assembly [ 35] and represented 180 unmatched patient specimens, including 40 normal breast tissues, 20 ductal carcinoma in situ (DCIS), 100 invasive ductal carcinomas (IDCs), and 20 lymph node breast cancer metastases [ 22].
Array testing results have indicated a steady progression of increased array tip operating fields with each new design tested.
By definition, the elements are excited with uniform amplitude, but they are allowed to have a phase progression across the array.
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