Sentence examples for progression and the development of from inspiring English sources

Activation of the Hedgehog signalling pathway contributes to cancer progression and the development of myeloid leukaemia stem cell therapeutic resistance.

To elucidate the structure and regulation of IP3R channels at the molecular level is of paramount importance to understand the disease progression and the development of targeted therapeutics.

Despite the significant increase in our knowledge on cancer initiation and progression, and the development of novel cancer treatments, overall patient survival rates have thus far only marginally improved.

The current report will also present several decision analytic models on the cost of atherosclerotic imaging including the evaluation of serial monitoring for disease progression and the development of cost-effectiveness models employing intermediate outcomes.

To conclude, the here presented SSC disease-in-a-dish approaches offer the unique opportunity to model SSC in human skin in vitro, which will allow further insight into SSC disease progression, and the development of therapeutic strategies.

This is a major obstacle to the understanding of disease progression and the development of therapeutics.

Higher resolution detection of CNV contributes to the basic understanding of tumor progression and to the development of biomarkers for prediction of response to therapy [6].

Such inflammatory mediators play an important role in fatal cases with fulminant progression and in the development of shock [ 5].

While the identification of biomarkers from biofluids or neuroimaging are invaluable for diagnosing PD, metabolomics can also provide insights into the molecular mechanisms of disease development and progression for the development of effective and personalized treatments of PD.

Several theories have been recently revisited with the development of a bad progression of sepsis and the development of recurrent infections in ICU [22].

Receptors and intracellular kinases are involved in cancer progression, metastatic spread and the development of resistance to pharmacological treatments [8].