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So, an improved comprehension of the precise molecular mechanisms leading to disease progression and design of effective targeted therapies are required for patients with breast cancer.
Detailed understanding of structural features of amyloid fibers is of great importance for our understanding of disease progression and design of agents for diagnostics or potential prevention of protein aggregation.
The illustration in this box shows the progression and design of RRS studies.
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Evidence from such a study can be useful in making decisions around progression to and design of the next stage of clinical development (large-scale, patient dose-ranging studies).
Taken together, the hypothesis proposed here may help understand the pathogenesis of tumor progression and design more effective strategy for clinical immunotherapy for tumors.
The identification of a gene variant that predisposes mice to renal deterioration after nephron reduction provides a candidate modifier for the elucidation of the complex genetic network that modulate human CKD progression and the design of prognostic biomarkers.
In other words, f1 has a high task difficulty (reflecting disease progression or design of instrument) and f2 has a low task difficulty (reflecting disease progression or design of instrument).
The increasing knowledge of the role of glycans in cancer suggests that further studies may assist both in determining their role in every step of tumour progression, and in the design of new therapeutic and diagnosic approaches.
Also, ADAM9D may be a tool for investigating the role of ADAMs in metastasis and cancer progression and for the design of selective inhibitors against the adhesion and extravasation of cancer cells.
Additionally, adequate modelling provides for enhanced understanding of disease progression, design of cell separation and drug delivery systems, and the development of biomaterials for tissue engineering applications.
Studies in lung fibrosis complicating SSc were unable to demonstrate efficacy, but this may reflect disease progression and trial design rather than lack of antifibrotic potential.
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CEO of Professional Science Editing for Scientists @ prosciediting.com