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The time to progression analyses showed significant differences between the three categories (P =.0167).
It should be noted, that although these tests were follow-up to the genes found significant in progression analyses, if a strict Bonferoni criteria considering all tests was used, these results would no longer be significant.
CAC progression analyses were repeated stratifying by age <65 and ≥65 years.
Cervical spine involvement of RA patients who were followed over time was included for the rate of progression analyses.
However, we were able to perform time to progression analyses that may also be used as measures of chemotherapy effectiveness.
Model 4 also included adjustment for the presence of baseline CAC for any CAC progression and advanced CAC progression analyses.
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All the parameters of cell cycle progression analysed were positive in suprabasal keratinocytes that expressed post-mitotic keratins K1 and K10.
Survival outcomes are commonly used, particularly in the cancer setting, with the time to an event such as death or disease progression analysed.
RECIST has been demonstrated to be useful in clinical trials where objective response was the primary study endpoint as well as in trials where assessment of stable disease, tumour progression or time-to-progression analyses were undertaken [2, 4].
There was, however, significant heterogeneity across trials for all time-to-progression analyses (P<0.00001, I=89.7%).
To identify predictors of radiographic progression, univariate analyses of baseline clinical and demographic variables were performed.
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