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Current therapies for epilepsy are largely symptomatic and do not affect the underlying mechanisms of disease progression, i.e. epileptogenesis.
There are three stages during disease progression, i.e., a normal state, a pre-disease state and a disease state.
A parametric finite element model is used to determine the influence of different material and geometrical properties on the failure progression, i.e. after initiation of damage.
At least two of the three readers found progression, i.e. at least two new lesions, in 120 patients and no progression in 135 patients.
Therefore, a prophylaxis treatment should be initiated early once patients with risks of progression, i.e., elevated migraine frequency and/or frequent acute medication intake, have been identified.
Extensive analysis of chromosomal translocations in human malignancies over the past three decades has revealed two main outcomes by which such rearrangements drive cancer progression: i) promoter exchange (mainly in lymphoid neoplasms), and ii) creation of chimeric genes that are translated as fusion proteins (myeloid leukemias and some solid tumors) [3].
Importantly, genes associated with cancer progression (i.e., Itgb2, Itgb5, paxillin, fyn) displayed increased expression, whereas those thought to suppress progression (i.e., vinculin, gravin) exhibited decreased levels of expression compared to MOSE-E cells.
More specifically this implies that the window period is the mean observable threshold crossing time, conditional on assay progression (i.e. actually reaching the threshold).
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There's a nearly fixed structure in pop music, and a best-selling chord progression, I-V-vi-IV.
The progression I-Vc-Ib must have the notes: doh-ti-doh in one inner part, and so-so-so in the other.
(A minor second is one note higher than the root note, a diminished fifth is six frets/half steps away, so if you play an open string, the note on the 6th fret of that string is the diminished fifth, etc).. Another common progression i-ii-i-VII-i (Although the ii chord is usually only a minor second from the root note rather than a whole step).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com