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Surgery basically involves the management of acute injuries and illnesses as differentiated from chronic, slowly progressing diseases, except when patients with the latter type of disease must be operated upon.
These are rapidly progressing diseases with often fatal outcome despite the use of high-dose methotrexate-containing treatment regimens [ 1].
The probability of clinical success for each type of intervention is undoubtedly crucial: for example, in rapidly progressing diseases in which the onset of the effect of treatment may be too slow once the disease is diagnosed, prevention may be viewed as a better strategy than treatment.
While some diseases, such as hepatitis B, do not require high circulating antibodies because of their slow pathogenesis (average incubation of 90 d), innate immunity and high levels of protective circulating bactericidal antibodies are the primary immune defenses against rapidly progressing diseases such as those caused by N meningitidis.
For more rapidly progressing diseases, if the time between patient observations is sufficiently small, the disease progression mechanics can potentially be estimated by a linear dynamics model.
The referral diagnoses were disability due to stroke, osteoarthritis, hip fracture and "others" (ageing disability, loss of function due to long periods of hospitalization and chronic, slowly progressing diseases).
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In contrast to healthy people, in later stage CF with progressing disease, microbial communities are clearly under selection.
Severe sepsis is a complex, multifactorial, and rapidly progressing disease characterized by excessive inflammation and coagulation following bacterial infection.
Treatment of chronic illnesses now accounts for almost 93%% of Medicare spending.1 Lymphedema, once acquired, is a lifelong progressing disease with no currently known cure.
My IBC sisters with progressing disease -- riddling their brains, their lungs, their livers -- were often in my situation only a short while ago.
Neuroinflammation has been widely regarded as a possible key player in progressing disease pathogenesis in various neurodegenerative diseases.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com