Sentence examples for progresses over decades from inspiring English sources

RA is a complex, polygenic autoimmune disease that progresses over decades and involves many different cell types, including both resident and recruited cells.

Development of gastric cancer, in particular the intestinal type, is a multi-step process that progresses over decades through premalignant lesions in the gastric mucosa, such as atrophic gastritis, intestinal metaplasia, and dysplasia [2].

Parkinson's disease (PD), an age-related neurodegenerative disorder, progresses over decades.

Disc degeneration is perhaps best defined as a cascade that begins with changes to the cellular microenvironment within the substructures of the disc that progresses over decades to structural breakdown and functional impairment (Freemont, 2009; Urban and Roberts, 2003).

Disc degeneration has perhaps best been defined as an aberrant, cell-mediated response to progressive structural failure (Adams and Roughley, 2006): a cascade beginning with changes to the cellular microenvironment within the disc that progresses over decades resulting in structural breakdown and functional impairment (Smith et al., 2011).

This process was predicted to be slow (progressing over decades), and thus implied a functional importance for mutations arising early in life [42].

Here Hollinghurst's structure begins to bear fruit, as we see events, personalities, and relationships whose progress we have witnessed over decades become flattened and distorted by Paul's literal-minded determination to correct the record.

In most cases the disease progresses slowly, over decades, and produces serious illness in only a small percentage of sufferers.

However, OA is a process that progresses slowly over decades, and small differences that may be inconsequential over short periods of time may have accentuated impact when assessed over years of chronic use.

Especially in attenuated phenotypes, a definite diagnosis may be delayed for years because early symptoms are difficult to recognize for physicians not familiar with the disease, since the disease progresses silently over decades.

The symptoms progress slowly over decades to include cognitive deficits and dementia.