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Despite the frenetic bio-medical progresses (more than 570,000 publications on PubMed using "biomarker(s)" term, of which about 40% are "cancer biomarker") and the substantial advances in the understanding of the molecular and bio-cellular basis of human diseases [ 25], a paucity of FDA-approved biomarkers is actually present [ 20].
The study will be terminated when the participant reaches skeletal maturity, defined as less than 1.0 cm growth of body height in 6 months, or if the curve progresses more than 6 degrees, compared to the primary x-ray, seen on two consecutive spinal standing x-rays taken with 6 months interval.
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The outcome measure can be the progression of raw scores or the number of patients that progress more than the smallest detectable change - for example, all patients that progress more than 6 points [ 14].
None, however, have progressed more than centers like Fairview.
But it also sets up an unspoken dynamic where incremental progress — more than contention — would make this season successful.
Gerrard, one of the Reds' greatest ever players, also believes that the 19-year-old has progressed more than he did at the same age.
Yet in the hands of corporations aiming to profitably serve the world's poorest consumers – the so-called base of the pyramid (BoP) – impact assessments can impede progress more than enable it.
A trial of three senior Khmer Rouge leaders now in progress, more than three decades after the killings, only underscores the country's deep amnesia: most Cambodians don't know much about the proceedings.
The group's singer-guitarist, Dave Mustaine, was once a member of Metallica; his contentious departure and the ensuing band rivalries accelerated metal's progress more than almost any other factor of the 1980s.
To make systematic progress, more than advocacy for adopting something new is required.
Study progress: More than 2,000 ACS patients were randomized as of June 2011.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com