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Despite advances in therapy, chronic heart failure (HF) is associated with an adverse prognosis 1 2 and progresses in the absence of overt clinical events.
In the well-known experimental murine model of RRV-induced BA-like disease, where the hepatobiliary disease progresses in the absence of detectable virus, the potential therapeutic use of MAPK blockers could be explored.
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In recent years, a bright spot of polio-eradication efforts has been Nigeria — a country that also raises some of the most challenging questions about sustaining progress in the absence of peace.
"They should be able to make progress in the absence of external influences because at the end of the day, it is a homegrown culture of rule of law that we are trying to promote.
* * * In recent years, a bright spot of polio-eradication efforts has been Nigeria — a country that also raises some of the most challenging questions about sustaining progress in the absence of peace.
Furthermore, Pten+/−ERα−/− mice showed a higher incidence of in situ and invasive carcinoma, suggesting that endometrial tumorigenesis can progress in the absence of ERα.
However, recurrent prostate tumors advance to an androgen-independent state in which they progress in the absence of circulating testosterone, leading to metastasis and death.
Fortunately, advances in DNA analysis technology allowed progress in the absence of a robust culture system.
In these conditions, it has been described that articular damage can progress in the absence of relevant disease activity [ 31].
To conclude, the surviving hepatocytes demonstrate an unaltered EMT progress in the absence of Caveolin-1 expression.
This allows the investigator to follow the evolution of the phenotype as the cell cycle progress in the absence of a particular protein.
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