Sentence examples for progressed to require from inspiring English sources
Many of the tumors that showed static somatic evolution and low methylation score changes progressed to require treatment quickly (<2 years).
He developed proliferative retinopathy, severe autonomic neuropathy with symptomatic gastroparesis, and diabetic nephropathy that progressed to requiring hemodialysis 11 months before the transplant evaluation.
The initiation of injectable therapy may represent an important milestone for the patient from both a clinical and personal point of view: in addition to the knowledge that their condition has progressed to requiring injectable therapy, the patient may be fearful of injections and side effects.
We examined separately the subset of patients who reached endpoint, and found that the differences between final and baseline scores for pS129 and pS129/α-syn ratio were somewhat larger, indicating that the changes are more pronounced in the subset of subjects that progressed to requiring levodopa therapy (Table 2; Figure 1).
However, many patients will progress to require additional therapies (combination oral agents and/or insulin).
Severe community-acquired pneumonia (CAP), defined as pneumonia acquired in the community area that rapidly progresses to require ICU admission, is a major infectious cause of hospitalization and mortality [ 1].
Such information could serve to better predict which patients may benefit from current medical therapy or are more likely to progress to requiring surgical intervention, as well as inform the choice of new medical approaches targeting novel pathways.
However, many people with diabetes progress to require antidiabetic medications.
Fujimura et al. [ 17] reported that two out of 43 patients with congenital TTP progressed to ESRD requiring dialysis.
Tsai et al. [ 7] reported that five out of nine patients with USS progressed to ESRD requiring dialysis, and three of them had episodes of ARF.
There were 23 fractures that progressed to non-union requiring further surgery.
