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Our findings suggest that some or all CIMF patients with JAK2 V617F might actually represent PV patients that progressed to myelofibrosis prior to diagnosis.
As increasing effort is dedicated to investigating the regenerative capacity of decellularized tissues, research has progressed to recellularizing these tissues prior to implantation.
Table 4 shows the medical costs for patients who progressed to higher stages of nephropathy prior to and following progression.
Parents may fear judgment from the medical team if the retinoblastoma symptoms have progressed to the point of disfiguration prior to presentation to care.
Exercise interventions included exercise therapy commenced in an inpatient ward and progressed prior to discharge to provide a programme of home exercises 33 and a 1.5 h training session twice a week.
Overall, out of the 39 assessable patients, 15 (38%) benefited from the chemotherapy regimen in terms of a reduction in mucus (with or without a solid component) or development of stability when known to be progressing prior to treatment.
5 In order to stratify for the effect of somatostatin analog treatment, patients were divided into those who were naive to octreotide (n = 115) to receive everolimus at a dose of 10 mg/day; and those who had previously progressed on octreotide prior to entry (n = 45) to continue with octreotide LAR in combination with everolimus at 10 mg/day.
In a phase III randomized study, 156 patients with HER2+ MBC who had progressed on prior trastuzumab were randomized to capecitabine alone or capecitabine plus trastuzumab.
As the reaction progressed and prior to collagen degradation, gelatin-like morphologies resulting from the denaturation of the triple helical collagen were observed.
Five patients progressed clinically and one patient progressed radiologically prior to the 3-month timepoint.
Thirty-one patients with advanced or metastatic non-small-cell lung cancer (NSCLC) that had progressed after prior systemic chemotherapy were eligible to receive oral gefitinib 250 mg/day as part of the EAP.
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