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Most CD11c+ cells in three-week granulomas were located in the lymphoid cuff, but as infection progressed the majority were distributed near the center of the granuloma (Fig. 2B), a common location for bacteria during chronic infection.
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Simply put, we cannot predict which lesions will progress (the majority) versus those that are unlikely to progress (a small subset, primarily in older patients).
In general, mice showed an increase in gene expression as infection progressed, whereas the majority of these genes were consistently upregulated or downregulated on days 1 and 6 p.i. in CA04 virus-infected macaques.
The disease inexorably progresses in the majority of patients, ultimately requiring insulin replacement therapy.
Unfortunately several investigations have shown that VF defects continue to progress in the majority of patients in routine clinical glaucoma care [ 11– 11].
Although two phase III clinical trials reported prolonged progression‐free survival in primary GBM, beneficial results appear to be transient as tumors eventually progress and the majority of patients does not benefit from an increased overall survival (Chinot et al, 2014; Gilbert et al, 2014).
As healing progresses, the majority of type III collagen formed by fibroblasts is converted to type I collagen to enhance soft tissue strength and integrity [5].
As the disease progresses, the majority of patients will require insulin to maintain HbA1c at desired target levels.
While some countries have made substantial progress, at the current rate of progress the majority of developing nations will fall well short of achieving the 2015 MDGs for maternal and child health.
They were environments where either the green revolution had never taken off (landraces constitute the majority of current cultivation) or, after initial success, there had been little further progress (the majority of modern varieties that farmers were growing were decades old).
However, once these initial problems were resolved the interviews generally progressed smoothly with the majority of residents saying that they had enjoyed taking part.
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CEO of Professional Science Editing for Scientists @ prosciediting.com