Exact(3)
Of the 39 who progressed (defined as progression or death within 3 months of the last scan), 22 patients (56%) first developed disease progression at a distant site, 5 patients (13%) at a local site, 6 patients (15%) experienced synchronous local and distant progression, and 6 patients (15%) died within 3 months of the last scan.
At FU 103 of the healthy individuals had remained at KL 0, and 25 individuals had progressed (defined as an increase in KL score by one or more grades).
When the sites progressed, defined by a 2 mm or greater increase in clinical attachment loss compared to baseline genes associated with pathogenesis, response to oxidative stress, and ferrous iron transport were highly expressed.
Similar(57)
The first principle is that every forward march is inspired by the emerging mass class, with progress defined in terms of its insecurities and aspirations.
But it still sees itself as just a tool, with the direction of progress defined by those who wield it.
Sites that completed more transformation activities and progressed over defined tiers reported higher PCMH-A scores.
For example, Corning has made remarkable progress defining its Digital Supply Chain vision and outlining the steps needed to move forward.
Much recent progress defining the molecular basis of phenotypic variability resulted from studying genomic DNA.
Although considerable progress defining the biochemical pathways regulating chromatin has been made, determining how these pathways are themselves controlled by environmental stimuli remains a major challenge in the field of epigenetics.
The second relies on a written commitment to progress through defined steps toward purchase.
Pregnancies were categorized as non-diabetes, GDM, progressing GDM (defined as GDM that progressed to T2DM within 3 months of delivery), or pre-existing T1DM or T2DM.
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