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As tissue capsule development progressed (days 14 21), myofibroblast-associated and pro-fibrotic genes (associated with TGF-β and Wnt/β-catenin signalling pathways, including Wnt 4, TGFβRII, connective tissue growth factor (CTGF), SMADs-1, -2, -4 and collagen-1 subunits) were significantly up-regulated.
Several exercises extended beyond this initial response and included scenarios that progressed days or weeks into an outbreak, requiring greater interactions between local- and state-level authorities and attention to health care surge capacity.
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Mr Hughes said at first he coped "hour by hour, minute by minute and slowly it's progressed to day by day".
As the infection progressed from day 1 through day 7 the HIV-1 RTase activity continued to increase (Fig. 1C).
As the mix progressed, the days settled into a kind of numbing, noisy rhythm.
The pneumonia progressed, and days later, she died.
The enhancing effect was largely over by the time the healing had progressed 14 days.
Kumon devised a basic study program that required the boy to complete one page of problems every day, progressing each day to a slightly higher level.
Usually, after HI and resuscitation cell death continue to progress for days and even weeks [29] and neurochemical changes may persist for several days [30].
High-grade glial tumours typically present with a short history of focal neurological deficit, which progresses over days to weeks and may mimic a stroke-like illness.
The collars transmit on a staggered three-day cycle so that Operation Migration is able to follow their progress day by day.
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