The ideal tumour marker should be (a) positive in patients only if malignancy is present or in progress, (b) correlated with stage and response to treatment, (c) repeatedly detectable, and (d) easily measured [ 1].
Zobrist finished a seven pitch at-bat, and the game, with a check swing for Strike 3. INSIDE PITCH Three infielders were in varying stages of progress with their individual leg injuries.
In the staged-progression model, individuals progress through disease stages with different infectivities, which represent the acute, latent, and AIDS stages of HIV infection.
A correlation of progressive decline in GFR with progressing stages of albuminuria has also been shown in the Joslin cohort (9).
In SPECTRUM, tumors progress through stages, with screening effects due to age- and stage-shifts and treatment reducing the hazard of death.
These studies included patients with stage I disease, who were unlikely to progress, and patients with stage IV disease, who had already progressed, and this may have confounded the assessment of the prognostic value of an elevated circulating C-reactive protein concentration.
Viola et al [ 3] reported that six of nine patients with stage I and all of the patients with stage II progressed to visual loss within 6 months.
Fruit from jars with no detectable ethylene remained at around 8 N, which is consistent with stage 89, whereas the fruit from jars producing autocatalytic ethylene had progressed to stage 92 and beyond, with a firmness of less than 4 N.
Repeated, staged testing of progress with the model introduces validity, reliability and rigour.
Analysis of nbr null animals reveals adult-stage defects that progress with age, including held-up wings, decreased locomotion, and brain vacuoles, indicative of accelerated age-associated processes upon nbr loss.
