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MGUS is common in the elderly but only a minority of MGUS individuals progress to develop symptomatic MM, with a frequency of progression of around 1% per year.
Considering the fact that many older adults with mild cognitive impairment progress to develop dementia, 60 interventions that delay this progression are increasingly important.
Atopy affects up to half of the adult population in developed countries; yet, the great majority do not progress to develop asthma [ 12].
However, due to their limitations, there is a progress to develop more reliable alternatives.
Experimentation and investigations are still under progress to develop a framework which can be applicable to a large number of various soccer leagues.
Indeed, attempts are currently under progress to develop a wide range of therapeutic proteins for treating various diseases including cancer, hepatitis and autoimmune conditions[1 4].
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Indeed class II isoforms of NRG1 have also found to be expressed in Schwann cell derived tumours [32], [34] and in a transgenic mouse model, expression of a class II isoform in Schwann cells led to mice developing hyperplasia with 60% progressing to develop tumours that resembled human malignant peripheral nerve sheath tumours [35].
Some of these subjects progressed to develop drug-induced autoimmune thrombocytopenia [ 6– 8].
Two patients progressed to develop visceral metastases, and one patient unfortunately succumbed to metastatic disease of bone, brain and viscera.
Control mice injected with the adenoX-lacZ control did not improve and progressed to develop a more severe arthritis.
She presented at 3 months with feeding difficulties and irritability and progressed to develop dystonia and rigidity in infancy associated with motor delay.
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