Sentence examples for progress to carcinoma from inspiring English sources
Oral epithelial dysplasia (OED) is a histologically detectable lesion that may progress to carcinoma but there are no accurate markers that predict progression.
Disruption of human APC in colonic epithelia initiates benign polyps that progress to carcinoma following additional mutations.
Oral leukoplakias are at increased risk to progress to carcinoma in situ and full-blown carcinomas or may even already display features of cell transformation [22].
For example, not all cases of DCIS progress to carcinoma and whether all patients with DCIS should receive adjuvant therapy after breast-conserving surgery remains a topic of active debate [47].
In this study, we also used another mouse model having an activated KrasG12D mutant allele that demonstrates hyperplastic polyp-like features, to investigate fluorescent-labeled peptide binding to a hyperplastic model that does not progress to carcinoma.
These scenarios might favor the increase of MIN detected in multiparous double transgenic mice that do no progress to carcinoma due to the senescence induced by AKT independent of p53.
The thyroid gland abnormalities in patients with CNC, display a broad spectrum of presentations, including follicular hyperplasia and/or cystic changes, and rarely progress to carcinomas [5, 10, 25, 29].
But a small proportion of these LGDs may progress to carcinomas [ 3].
Mutations in KRAS2 can initiate the development of pancreatic cancer [ 40] but the same mutations may result in hyperplasia in the colon [ 41] or borderline lesions that do not progress to carcinomas in the ovary [ 42].
Paraffin sections of 41 OED cases that progressed to carcinoma, 40 OED without malignant progression, 38 OSCC and 15 NOM were immunostained with antibodies against Mcm2, geminin and Ki67.
The final total of 134 cases selected for analysis comprised 41 OED that had progressed to carcinoma, 40 OED that did not show malignant progression, 38 OSCC from the 41 cases that had progressed and 15 samples of NOM.
