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In general, although it is easy to consider some possibilities that the loci in non-synonymous sites would cause variations in protein sequence and possibly cause the change of protein structure, to verify the biological effects of the identified selective loci will lag behind the progress of identifying selective loci in the next several years.
We have combined these mutants under the name Salsa (Table 1 and Fig. 2) and are still in the progress of identifying the causative mutation.
In comparison, the progress of identifying biological mechanisms, drug development, and strategies for effective prevention and intervention in response to depression has been relatively slow [22], [23].
Another factor likely impeding the progress of identifying COPD susceptibility genes is the lack of accurate phenotypic characterization of this complex and heterogeneous disease.
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We highlight the recent elucidation of the X-ray structures of key membrane enzymes of glycerophospholipid synthesis, progress on identifying lipid scramblase proteins needed to equilibrate lipids across membranes, and new complexities in the subcellular location and membrane topology of phosphatidylinositol synthesis revealed through a comparison of two unicellular model eukaryotes.
The current progress and methodology of identifying genotypes that underlie human phenotypes has been reviewed in detail.
The evaluation element inferred an assessment of progress or lack of progress (identifying gaps) in terms of applying the conditions.
"This is great progress toward our objective of identifying magnet materials and technology that can deliver the performance our customers expect while limiting our exposure to price and supply concerns associated with rare-earth magnets".
Together, these improvements allowed us to make progress on the problem of identifying sequence determinants of gene expression variation (Yuan et al. 2007).
DNA sequencing is used to diagnose genetic and infectious diseases, discover drugs, characterise environments, monitor the progress of cancers, identify species and reveal evolutionary patterns.
It shifted too much control away from state and local elected officials, diluted the impact of federal resources, and relied on a method of identifying academic progress that focused on failure instead of rewarding excellence.
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