However, with respect to long-term outcome, it is known that bone plasmacytoma progresses more frequently to multiple myeloma (MM) than soft-tissue plasmacytoma [ 7- 9].
Despite establishing homology in 98 or 96%, U-CLL patients presented with a higher initial white blood cell count (WBC) (median 31.5 × 10/L versus 21.2 × 10/L; P = 0.038) and higher levels of LDH (P = 0.003), belonged to advanced Binet stages (P = 0.001), progressed more frequently (P < 0.0001), and had a shorter leukocyte duplication time (P = 0.001).
As her career progressed, Ferreira more frequently experimented with elements of indie rock, which were commonly heard in her debut album Night Time, My Time.
BTK inhibitor ibrutinib proved effective in this cytogenetic subset, however it is worth noting that, possibly due to clonal evolution, those patients with 11q− or 17p− may progress under ibrutinib more frequently than patients without 11q−/17p− 9. Likewise treatment by idelalisib and ABT-199 proveffectiveirrespectivetive of the presence of 11q− 58, 58.
Despite good local control with RT, patients with bone SP progresses to MM more frequently than those with extramedullary SP [ 7, 10].
While V600EBRAF-driven early lung lesions with OIS rarely progress to adenocarcinoma (Dankort et al, 2007), G12VKRAS-driven alveolar hyperplasias progress into malignant adenocarcinomas more frequently (Mainardi et al, 2014), which correlates well with the mutation spectrum of human lung adenocarcinomas.
Oxnard GR et al. reported that patients with tumors harboring T790M mutation had more favorable outcomes, and that those without T790M more frequently progress to previously uninvolved organs.
A significant increase in the BSFC-s score was observed when dementia progressed, disturbing behavior occurred more frequently, care requirements increased, and when caregivers were diagnosed with depression.
Patients with NPC more frequently progressed to disease-specific mortality with N2 N3 nodal status (p=0.002) and stages III IV (p=0.007) (table 3).
The fortunes of this war during its progress shifted constantly and were, more frequently than not, adverse to the Romans.
