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By implementation of novel genotyping technologies, progress in delineating the genetic architecture of acquired liver diseases has been achieved in recent years.
This review comprehensively summarizes current progress in delineating the roles of miRNAs in MM pathobiology and management.
Although more than 200 genes are known to cause NTDs in mice, there has been rather limited progress in delineating the molecular basis underlying most human NTDs.
Only through the careful pathological assessment of such cases, however, often assisted by new pathological techniques (for example, new antibodies, genetic probes), will progress in delineating new or newly recognised diseases evolve.
In addition to stimulating significant progress in delineating the molecular mechanisms causing cervical cancer, this observation led to the development of an effective vaccine that is now widely used in many countries [ 2].
While studies to date have made tremendous progress in delineating the brain mechanisms supporting persistent pain in FM patients, future studies will need to better link neuroplastic change in the brain with both pain and non-pain clinically relevant outcomes.
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Over the past 10 15 years substantial additional progress has been made in delineating risk factors for breast cancer.
In the last fifteen years, rapid progress has been made in delineating the cellular response to DNA damage.
Increasing progress has been made recently in delineating the cellular and molecular mechanisms underlying tubulogenesis.
Substantial progress has been made in the last quarter-century in delineating the mechanisms by which thermal stress and photoperiod influence performance of dairy animals.
While this is still work in progress, we think it abundantly illustrates what is ahead of us in delineating genetic variation that underlie complex disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com