Sentence examples for programs that govern from inspiring English sources

Our work demonstrates engineering of fully functional HSCs via modulation of genetic programs that govern self-renewal and lineage priming.

We show that the loss or gain of transcription factor programs that govern embryonic cell-fate specification is associated with a form of tumor plasticity characterized by the acquisition of alternative cell fates normally characteristic of adjacent organs.

This suggests that stem and progenitor cells have distinct programs that govern which targets are available for miR-126 to influence, resulting in differences in signaling responses within each cell type.

The identification of gene signatures that predict response to chemotherapy also have potential to offer new insights into the biology of breast tumors, particularly the transcriptional programs that govern therapy response.

Although a first draft genome sequence was released in 2007, very little is understood about transcription programs that govern developmental changes required for the parasite's development and survival in its mammalian and insect hosts.

Observation of neurological symptoms detected either at birth or during early childhood raises the possibility that CSB may have a crucial role in the transcriptional programs that govern the plasticity and the maintenance of the central nervous system during (perinatal and postnatal) pediatric life.

DOI: http://dx.doi.org/10.7554/eLife.04236.002 The existence and importance of long-range interactions between distal cis-control elements and cognate core promoter factors in regulating gene expression programs that govern cell-fate in animals have been extensively studied in traditional biochemistry, genetics, and genomics (Levine and Tjian, 2003; Levine et al., 2014).

Significant strides in the analysis of gene expression have been made in recent years, revealing the regulatory programs that govern the fate of individual neurons, their interactions with diverse ligands, and their ability to adapt to changes, such as environmental cues and injuries (Schreiner et al., 2014).