Sentence examples for programs activated by from inspiring English sources

The gene expression programs activated by these pathways initiate a spectrum of fundamental cellular activities including proliferation, growth (increase in cell size), differentiation, and survival [ 64, 65].

However, little is known about the transcriptional programs activated by NOTCH1.

Characterization of the critical transcription programs activated by Ang II in vivo and determination of the hierarchy of responses are vital to the understanding of the mechanism of vascular disease and to the development of therapies targeted at inhibiting the common transcription effectors of vascular pathology.

To provide indications for the cellular programs activated by the compounds we performed GO assignments of the transcripts using DAVID analysis platform [24], [25].

Target genes regulated by the HH signaling pathway differ between tissues and cell types, as well as being influenced by the presence or absence of regulatory factors co-expressed with GLI proteins that eventually determine the transcriptional programs activated by HH signaling [6], [37].

Apoptosis and I-kB kinase/NF-kB cascade are two main programs activated by TNF.

Okabe, Y., Kawane, K., Akira, S., Taniguchi, T. & Nagata, S. Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation.

We then elucidated the role of the early infiltration of anti-inflammatory Mϕ, into the scaffold, their retention in situ, and the simultaneous release of anti-inflammatory cytokines as part of a distinct regenerative program activated by the CSCL scaffold.

Overall, these findings identify transcriptional control of PTEN and regulation of the PI3K-AKT pathway as key elements of the leukemogenic program activated by NOTCH1 and provide the basis for the design of new therapeutic strategies for T-ALL.

Given that their expression changed before any biochemical evidence of proliferative arrest or apoptosis, these genes might be part of an anti-proliferative signaling program activated by gefitinib.

To address this issue, we sought to identify the genetic program activated by β-catenin in neurons.