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Our observation that heart weight is increased at 8 wk of age demonstrates for the first time that cardiac hypertrophy precedes differences in body weight and adiposity in the offspring and that it is therefore not a consequence of those differences but a programmed effect resulting from exposure to a suboptimal environment in early life.
5. Synthy, electronic mid/fast beat, lots of programmed effect and other sounds, Postal Service, juxtaposed with plain vox.
Unlike the better-known changes called mutations, epigenetic changes do not alter the underlying genetic code, but they do affect whether or not a gene has its programmed effect, for good or ill.
Responses that occurred during the interval were recorded but had no programmed effect.
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This study could not detect a "programming" effect of early nutrition supplementation on adult LBM and muscle strength.
The effects of prenatal interventions on postnatal growth suggest programming effects in early fetal life.
Furthermore, administration of dexamethasone or carbenoxolone reduces birth weight and exerts programming effects in rats [21,35,150,198,200,255,298,299,306,307].
Genetic effects, programming effects in utero and differentiation effects after birth may account for these prenatal and postnatal associations [ 10].
The effects of these prenatal nutrition interventions on postnatal growth suggest programming effects in early fetal life.
Recent work also suggests that the microbiota has acute as well as programming effects on the brain and behavior.
We speculate about the potential reasons for the differential program effect across high schools.
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CEO of Professional Science Editing for Scientists @ prosciediting.com