Frequent screening at a young age decreases the programme's specificity given that every screening round adds to false positive test results (that is, the detection of non-progressive HPV infections or cervical intraepithelial neoplasia lesions), and screening at a young age detects many transient infections and abnormalities.
But if the Grand Challenges programme loses that specificity, and gets buried in the groupthink which pervades the field of international do-goodery, then a valuable alternative approach will, from a scientific viewpoint, have been lost.
These consequences resulting from an erroneous positive identification could be considered as negative side effects of a screening programme with insufficient specificity.
3. Falla D, Lindstrom R, Rechter L, Boudreau S, Petzke F. Effectiveness of an 8-week exercise programme on pain and specificity of neck muscle activity in patients with chronic neck pain: A randomized controlled study.
PCR was set up in a GeneAmp PCR system 2400 (Applied Biosystems, Courtaboeuf, France) with a touchdown programme to increase the specificity.
However, when we designed the questionnaire we felt that anyone supporting a screening program has to be familiar with the health problem targeted by the program, the features of the test involved (sensitivity and specificity) and the programme expected benefits.
Breast cancer was diagnosed in 485 women (detection rate 0.52 %); 253 interval cancers were reported, yielding a programme sensitivity of 66%% and specificity of 99%%.
Education in the field of paediatric palliative care deserves careful consideration regarding the appropriate form, extent, and specificity of the programme.
In the model, a positive or negative screening result was assigned based on the presence or absence of BC in each woman and the corresponding sensitivity and specificity of the programme.
However, training programmes differ greatly in occupational specificity.
