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A multicohort programme of vaccination using the quadrivalent vaccine was associated with a total saving of approximately €132 million, as a result of a reduction in the numbers of low-grade and high-grade cervical lesions, anogenital warts and invasive cervical cancers (table 1).
The results of their study suggested that the introduction of a programme of vaccination using a quadrivalent HPV vaccine alongside the current programme of screening for cervical cancer in Italy would produce an incremental cost effectiveness ratio of €12 303 per life year gained and €9569 per quality-adjusted life year gained.
For this reason, we believe that any programme of vaccination with RIX4414 or other rotavirus vaccines with comparable cost and efficacy should be viewed as only a temporary solution until less expensive vaccines derived from native strains can be manufactured regionally.
We should have absolute confidence in our national programme of vaccination.
And, Ali says, the real difficulty is still to come: ensuring that once the emergency operations against polio are over, a regular programme of vaccination for all childhood diseases is put in place when the international community turns its attention away.
With hindsight, it is clear that an entirely new approach needs to be developed in which the medical community, ie practitioners and relevant scientists, should be included in any programme of vaccination and, armed with appropriate information, they should be charged with the responsibility of explaining the importance and significance of vaccination within their local communities.
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However, the model does not resolve all the issues related to the cost effectiveness of such programmes of vaccination.
Programmes of vaccination, aimed at reducing the burden of cervical cancer, may also help to reduce the incidence of cancers of the vulva, vagina and anus in women.
To date, no studies have examined specifically the level of allocative efficiency of resources assigned to programmes of vaccination against HPV.
Programmes of vaccination against HPV, aimed at reducing the burden of cervical cancer, may also help to reduce the incidence of cancer at other anogenital sites.
In 1998, a programme of universal vaccination of preadolescents in schools with the hepatitis A vaccine was begun in Catalonia.
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