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Indeed one of the early concepts of cancer was that it was initiated from embryonic-like cells or embryonic 'remnants' [ 57] in which this program was reactivated.
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In normal adult tissues, the typically dormant EMT program is reactivated during wound repair and tissue regeneration.
Interestingly, the miRNA signature of failing heart has a similarity to that of fetal cardiac tissue; this is in accordance with the idea that during heart failure, the fetal-gene expression program is reactivated.
What distinguishes cancers is that these programs are reactivated inappropriately and evade the normal controls.
In response to tissue loss, silenced developmental programs are reactivated to form a near-perfect copy of the missing body part.
In September 1975, the 24th Infantry Division was reactivated at Fort Stewart, Georgia, as part of the program to build a 16-division US Army force.
Then Peca was reactivated.
The flushing tunnel was reactivated in 1999.
The fault was reactivated extensionally at 121±5Ma.
The grant was reactivated, and the council found £750,000.
Its Facebook account was reactivated on Tuesday evening.
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