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The Bridge to the Doctorate Program (terminal master's to doctoral bridge) served 102 educational institutions in 23 partnerships.
However, the genes that program terminal differentiation in these apoptosis-resistant malignant cells can be silenced by epigenetic mechanisms, such as DNA methylation, and reactivated by non-toxic doses of 5-AZA-CdR.
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Originally, PLC manufacturers provided dedicated program terminals that were specific to their PLCs.
We show that ectopic expression of a type III IF protein in basal keratinocytes did not interfere with the normal epidermal architecture and the program of terminal differentiation.
The epidermis is a self-renewing stratified epithelium mainly composted of keratinocytes that undergo a complex and dynamic program of terminal differentiation throughout life [44].
During bone growth a subset of slowly proliferating chondrocyte progenitors within the growth plate continuously enter into a program of terminal differentiation, where they first undergo proliferative expansion and then undergo hypertrophy and die.
To serve these functions, epidermal cells undergo constant renewal in a highly regulated program of terminal differentiation.
These data suggest that keratinocytes, when depleted of TCF7L1 expression, prematurely initiate a program of terminal differentiation in OTC.
In contrast with the transcriptional program of terminal granulocytic differentiation [ 46], chemokines in SF PMN from patients with RA were not upregulated in parallel with their receptors.
These interactions determine the positive and negative selection events that are crucial components of the program of terminal thymocyte differentiation [ 4– 6].
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