Sentence examples for prognostic signatures from inspiring English sources

Data from genomic profiling enabled a proposal of HCC in 2 major molecular clusters (proliferation and nonproliferation), with differential enrichment in prognostic signatures, pathway activation and tumor phenotype.

We also added pre-defined prognostic signatures from previous publications [6], [10].

These studies aim to identify novel cancer-related genes and to define novel biomarkers for response or prognostic signatures.

Our study also highlights the importance of the large sample size in microarray analyses for identifying and validating prognostic signatures.

These represent 19 prognostic signatures, two signatures focused mainly on metastasis, and seven predictive treatment response signatures.

Compared to previously published prognostic signatures for NSCLC, the 17 gene signature performed well on these two cohorts.

We assessed the performance of these previously reported prognostic signatures on the Erasmus MC and Duke University data sets.

The issue of concordance [21] or lack thereof [17], [22] between different prognostic signatures was also debated.

Hazard ratio and concordance probability estimate (CPE) were used in the evaluation of different molecular prognostic signatures.

Finally, in many instances it is not clear if the prognostic signatures reflect reproducible stable disease phenotypes or are simply a combination of prognostic genes.

The fact that there is very little if any overlap between the genes of different prognostic signatures for early-discovery breast cancer is well documented.