Exact(17)
Earlier diagnosis and prompt treatment should improve the prognostic outlook.
The prognostic outlook was more optimistic for women with breast cancer when they were between 35 and 75 years old.
Heart failure is a complex syndrome associated with reduced quality of life and poor prognostic outlook [ 1- 3].
(13) Overexpression of HER-2 is typically correlated with higher aggression and a poorer prognostic outlook in breast cancer.
Whilst membranous HER4 was associated with a good prognostic outlook, nuclear HER4 was associated with significantly shorter survival times [ 16].
Traditionally, stage groupings from I to IV have been used to divide patients into groups of decreasing suitability for treatment with curative intent and, consequently, worsening prognostic outlook.
Similar(43)
A variety of prognostic factors determine outlook in these patients (Motzer et al, 1991; Gerl et al, 1995; Miller et al, 1997; Loehrer et al, 1998; Fossa et al, 1999).
However, the application of a continuous score to estimate the prognostic index and hence the outlook of a given patient does not require grouping and may be preferred by some as the primary way to apply the model.
4, 5 For patients with poor prognostic features, as defined by the Memorial Sloan Kettering Cancer Center MSKCCC) staging system, the outlook can be even more grim with median survival of 4 months and few patients surviving 1 year.
The prognostic factors are largely established; patients with four or more metastases have a worse outlook as do patients with larger metastases and where the primary tumour is poorly differentiated or has lymph node involvement.
The clinical course described in these reports suggest a poor prognosis for MDS/sPAP patients, but no prior report clearly quantifies the outlook for these patients and compares this to a predicted outcome by using validated prognostic scores such as WPSS.
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