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I am not trying to shift the burden of prognostic knowledge from the physician to the patient.
And I believe that the poor state of prognostic knowledge and prognostic practice is a factor that is contributing to these bad outcomes.
There are few efforts to systematize prognostic knowledge.
At this juncture carefully designed studies are critical in order to gain solid diagnostic, therapeutic, and prognostic knowledge about the role of antibodies in graft injury and to avoid any confusion and misconception.
In this situation, prognostic knowledge can only be deepened by large-scale multicentric studies with a high enough number of abnormal cases with follow-up data.
In conclusion, we very much welcome the authors' effort aiming to reduce prognostic uncertainty in the challenging group of patients with VS/UWS [ 1] and emphasise that no good medical (and ethical) decisions can be made in the absence of good clinical and prognostic knowledge [ 14, 15].
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They were helped by knowing the views that the person with dementia held before losing capacity about what they would want in this situation, as well as by clear prognostic information, knowledge about future quality of life, and family support.
To our knowledge, the prognostic or predictive impact of PODXL expression in pancreatic or periampullary adenocarcinoma has not yet been described.
The future of mCRC research will involve optimizing the sequence of currently proven therapies while incorporating novel agents, as well as further translational work to build upon current knowledge of prognostic and predictive biomarkers and to identify additional druggable targets.
To our knowledge, no prognostic or predictive biomarkers have yet to be prospectively validated in multiple independent studies to reliably distinguish patients with advanced RCC who are likely to respond from those who will not.
To the best of our knowledge, many prognostic studies including people with ICU-acquired muscle weakness used a rather conventional prognostic design using a baseline test and compared with ICU discharge and follow-up data 6 36 37 and just some studies measured functional recovery continuously over time.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com