Exact(13)
This study evaluates the prognostic impact of all known human angiopoietins (Ang-1, Ang-2 and Ang-4) and their receptor Tie-2, as well as their relation to the prognostic expression of VEGF-A.
Our primary objective was to investigate whether lncRNAs had a prognostic expression pattern that defined the metastatic phenotype.
Analysis of a prognostic expression profile was performed in 89 primary pleomorphic tumors, mostly including MFH/UPS and leiomyosarcomas.
Notably, several tumor suppressor genes have undergone different mutational events in different tumor regions and also different tumor regions harbored different good and bad prognostic expression signatures.
The intersection between gene amplification and over-expression has also been exploited to uncover transcriptional regulators of a prognostic expression signature in breast cancer.
After completion of our literature search, the ClearCode34 prognostic expression signature was published that is based on the ccA/ccB signature [38].
Similar(47)
Expression of the PTTG1 gene was among the most significant components within the prognostic gene expression signature in prostate and breast carcinoma.
Our data indicate that the prognostic gene expression signatures are present at the time of diagnosis.
In this study, we identified and validated a prognostic gene expression signature in DCs associated with inflammation.
The robustness of the prognostic gene expression signature was validated in an independent cohort using the reduced gene set.
It is frequently unclear if prognostic gene expression models are surrogates for underlying wider molecular or biological phenotypes, or simply a combination of individual prognostic genes.
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