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Thus, there are still major diagnostic and prognostic challenges for periodontal diseases.
As Ov-induced ICC poses unique diagnostic and prognostic challenges, an accessible early diagnostic marker in blood is greatly needed.
It is also vital for the medical community in which physicians are constantly faced with the diagnostic and prognostic challenges of CAP patients with uncommon pathogens.
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Since early rheumatoid arthritis (RA) is often indistinguishable from other inflammatory joint diseases, recent-onset inflammatory synovitis poses a diagnostic and prognostic challenge to rheumatologists [ 1].
Another prognostic challenge is to identify patients among the currently high-risk ER-positive cancer cases (high recurrence score or luminal B molecular class) that are no longer at high risk after receiving adjuvant chemotherapy [ 30].
The PCoE addressed the following prognostics challenges: uncertain management; autonomic control reconfiguration based on prognostics output; integration of different and sparse data collected from interconnected subsystems to be processed; prognostics system validation and verification; post-prognostics reasoning.
This unification is not yet considered by the research community, although it will help to fill the gaps in prognostics technology and create an integrated effort to resolve prognostics challenges.
The frequent finding of subtype specific prognostic features challenges the concept of molecular classifiers that apply to all prostate cancers.
34 The finding that voluntary early retirement and disability pension only has few mutual prognostic factors, challenges common notions of a retirement process driven by work-related or health-related factors.
Long-term prediction, data trending correctness, variability in external affecting factor that is difficult to be quantified [65], availability of run-to-failure data, accelerated aging test for off-line algorithm evaluation, developing of real-time algorithm [66], prognostics requirement specification [11], and prognostics standardization are also challenges.
A large grain of inherent uncertainty imposes major challenges in prognostic methods development.
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