Exact(7)
The combined score of the two poor prognosis parameters with the lowest scores was more than the cutoff value.
Bmi-1 expression is often deregulated in several types of human cancer, including hematological and solid tumors, which correlate with poor prognosis parameters.
Disturbed Bmi-1 expression has also been reported, and correlates with poor prognosis parameters, in solid tumors such as lung cancers [ 34], medulloblastomas [ 35], neuroblastomas [ 36], liver [ 37], breast [ 38], colon [ 39], nasopharyngeal [ 40], and prostate [ 41] carcinomas.
In our series, 13% of tumors showed NHERF1 still localized in the plasma membrane, and were positively associated with favorable prognosis parameters, such as low tumor grade, positive PR status, and low proliferative activity.
146 EGFR amplification is frequently associated with poor prognosis parameters in breast cancer patients, such as large tumor size, high histological grade, high proliferative index, and negative estrogen receptor status.
Good prognosis parameters are: progression-free interval of > 2 years, CR to induction treatment and normal or low serum markers at relapse (hCG < 100 IU l−1 and AFP < 100 kU l−1).
Similar(53)
In addition, we have recently reported that CRT measured on the knee area was a better prognosis parameter than CRT measured on the finger tip [11].
In conclusion, TAR on MR images after neoadjuvant chemotherapy was the only parameter that predicted prognosis among parameters for tumor size.> -wrap-foot> Abbreviations: HR hazard ratio, CI confidence interval, ATL absolute tumor length, ATV absolute tumor volume, RTV relative tumor volume, ATA absolute tumor axial size, TAR tumor axial ratio.
Several staging systems have been proposed to predict patient prognosis, including parameters such as functional liver reserve, performance status, circulating tumour markers, and extent of spread of the primary tumour (Bruix et al, 2001).
In another study, the persistence of microsatellite alterations in plasma DNA of post-mastectomy patients has been associated with bad-prognosis histological parameters and indicated micrometastatic disease [ 30].
Multivariate analysis against the prognosis-associated parameters gender, age and TNM classification showed that the MMP-2 SNP was independently associated with survival, whereas the tumour protein levels of MMP-2 just lost and MMP-9 completely lost their significance.
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