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Conceptually, why are they dead (i.e., in your own words, what is it about loss of brain function, including the brainstem, that makes this patient dead)?" For analysis, we classified responses into categories that have been discussed in the literature, including loss of integration concept of BD, higher brain concept of BD, prognosis concept of BD, and statement of the criterion only.
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The following key issues arose from the data synthesis: the importance of patient prognosis; the concept of "appropriateness"; "benefits and burdens" of diagnosis and treatment; LMWH or warfarin for treatment and sources of information which changed practice.
Examining the newer data from GOG218 and ICON7 more closely suggests that bevacizumab does not benefit patients who are optimally debulked (i.e., better prognosis), supporting the concept that different disease 'stages' could influence the response of tumours to anti-vascular interventions.
Christian theologians spent the best part of two millennia sorting out these implications and devising ways out of the dire prognosis implicit in the concept of original sin.
The concept of prognosis dates back to antiquity.
For example, the concept of "prognosis" may differ between health care provider groups.
The weight of co-morbidities on patients' prognosis is a usual concept in several fields of medicine.
This may reflect normal myocardial tissue in this AS group with an excellent prognosis, and supports the concept that the myocardial response is an important part of the progression to more symptomatic disease.
IgG4-related sclerosing disease is a relatively new disease concept, and its prognosis has not been well described.
15 Some of the long-term postsurgical follow-up studies supported the concept that the prognosis may improve over time, for example, less memory decline.
Communicating the dynamic, often intangible, concept that is prognosis is pmount, as is doing so in a way that is patient-centered and specific.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com