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Progenitors that have not previously expressed PLZF generate the LTi cells in a RORγt-dependent manner.
Wnt1-CreERT and tamoxifen administration were used to mark progenitors that contributed to the trigeminal ganglia.
Researchers in the 1960s hypothesized that modern cells evolved from progenitors that didn't require this interdependence.
Neural stem cells (NSCs) are multipotent, self-renewing progenitors that generate progeny that differentiate into neurons and glia.
Several Wnt and sonic hedge-hog inhibitors, which are being evaluated in preclinical models, show promise clinically for eradicating committed progenitors that have aberrantly gained self-renewal capacity.
Initially, the cardiac progenitors that derive from the primary heart field migrate toward the midline of the embryo to fuse and form the primary heart tube.
Further studies are also needed to delineate the relationship(s) and functional distinctions (if any) between renal progenitors that are positive for different antigen combinations.
By manipulating the molecules bathing ES cells, they hope to create progenitors that will turn into motor neurons when transplanted.
Thus, cotreatment with TKIs and DT388IL3 is much more effective in eliminating Ph+ leukemic progenitors that express IL-3R than either agent alone.
Skeletal muscle's restorative properties lie in its satellite cells: progenitors that have the capacity to turn into and replace the damaged muscle.
Stress erythropoiesis relies on a specialized population of stress erythroid progenitors that are primarily resident in the spleen[2].
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