Sentence examples for progenitor model from inspiring English sources
The progenitor model used here is still somewhat artificial in construction, with a constant mass loss parameter late in its evolution.
As understanding of Type Ibc progenitors improves (for some recent investigations, see Kim et al. 2015), future work would benefit from a more realistic progenitor model by modelling the mass loss processes in detail.
Given the high connectivity of these gatekeeper modules, it is a reasonable inference that tumor cells could exploit the epigenetic plasticity within these key modules and thus gain a drug resistance phenotype, as suggested by the 'phenotypic plasticity' hypothesis [26] and the 'epigenetic progenitor model' of cancer [25].
It fits our epigenetic progenitor model [ 11] beautifully.
I think the epigenetic progenitor model [ 11] changed a lot of people's minds though.
Feinberg et al (2005) proposed a model for the origin of CSCs and therefore carcinogenesis: the epigenetic progenitor model of human cancer [ 153].
These data support a luminal multilineage progenitor cell model for prostate tissue and establish a robust, scalable system for mechanistic studies.
However, the human progenitor hierarchy model was recently fractionated into more precise subpopulations (Doulatov et al., 2010; Notta et al., 2011).
This study demonstrates how the regulation of differentiation can be understood using a primary human progenitor cell model with traditional techniques and novel high content imaging, proteomic and computational methods.
Looking backward in time, the clones either had a constant per generation probability P' of being founded by a single ancestor derived from a sexual progenitor (neutral model), or this probability raised per generation at rate [1 - (1 - f') a'], where a' denotes the age of clonal lineage and f' is the rate of fitness loss (the decay model).
MyoD-Cre and Tie2-Cre reporter mice have been previously employed to study the contribution of endogenous myogenic and vascular progenitors in models of heterotopic bone formation [ 10].
