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Lawall H, Bramlage P, Amann B. Stem cell and progenitor cell therapy in peripheral artery disease.
Cao, W. et al. Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease.
Various stem cell types are being evaluated in preclinical and early clinical applications; here, we review the preclinical strategies and advances supporting the recent clinical translation of neural progenitor cell therapy for ALS.
Endothelial progenitor cell therapy for atherosclerosis: the philosopher's stone for an aging population?
The first, progenitor cell therapy, is limited by the low viability and integration of transplanted cells.
To estimate the impact of progenitor cell therapy for atherosclerosis on cardiovascular disease (CVD) mortality, life expectancy, and survival, as compared with the lifetime control of conventional risk factors, we modeled the health effects of bone marrow-derived endothelial progenitor cell therapy using data from the 1950 to 1996 follow-up of the Framingham Heart Study.
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This article provides an overview of the current status and efficacy of stem and progenitor cell therapies that include cultured and nonexpanded sources such as bone marrow, adipose tissue, synovium, and peripheral blood.
Progenitor cell therapies show great promise, but their potential for clinical applications requires improved storage and transportation.
Topical lineage-negative progenitor-cell therapy for diabetic wounds.
CONCLUSION: Topical progenitor-cell therapy successfully accelerates diabetic wound closure and improves wound vascularity.
More specifically, along with traditional therapeutic approaches for LSDs involving substrate reduction or gene therapy, new paradigms such as glial progenitor cell replacement therapy or modulation of neuroinflammation can also be considered in MLIV.
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