Then, after they've loosened up, they can manipulate time in almost the opposite direction, profoundly slowing their process down.
By contrast, in the two problem gambler groups, AMPH improved reading speed to Gambling words while profoundly slowing reading speed to motivationally irrelevant Neutral words.
The majority of the early onset hereditary neuropathies represent demyelinating phenotypes with sometimes profoundly slowed motor nerve conduction velocities, indicative of severe demyelination or even amyelination.
For example, there is a great deal of evidence that the rapid uptake of glutamate that occurs in adult neuronal tissue is profoundly slowed early in development due to a delay in transporter expression (Thomas et al., 2011).
For example, the elimination of the dominant RGS in rod photoreceptors profoundly slows deactivation kinetics while minimally affecting response amplitude or sensitivity (Chen et al., 2000; Krispel et al., 2006), whereas in hippocampal pyramidal neurons, moderate changes in response kinetics are accompanied by increased sensitivity (Xie et al., 2010).
Yet in a morbid way one feels something benign in the separate existence of this profoundly terrifying slow movement.
Into that landscape come three exciting newcomers that are changing the market much more profoundly than the slow-moving incumbents yet realise.
Filmmaking is profoundly unglam orous - slow, repetitive, uncomfortable - and on set stars forgo glamour and get on with the job.
Fischer's performance of no 9, the New World Symphony, is not for sentimentalists: the tone is often brooding, the slow movement profoundly tragic, and the scherzo nervously energetic in the extreme.
Hedy Weiss wrote in the Sun-Times "Really, what could Steppenwolf have been thinking?," saying the play "sends out a slew of profoundly misguided messages to its impressionable viewers".
