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All this activity has profoundly modified drama as literature.
In heavily settled regions the makeup of plant and animal life has been profoundly modified.
In the same book, he includes a letter he wrote in 1960 to his German translator, in which he announces that his time in the Lager, and writing about the Lager, "was an important adventure that has profoundly modified me".
Jewish thinkers in Muslim Spain and the Maghrib adopted Aristotelianism (as well as systems that stemmed from but also profoundly modified pure Aristotelian doctrine) considerably later than did their counterparts in the Islamic East.
Opinions may differ widely as to the balance of advantages or disadvantages, from the European and the African point of view, which have resulted from the irruption of the Great Powers of Europe into the African Continent, but no one can doubt that in shaping events that have so profoundly modified recent history Mr Stanley played a considerable part.
The use of these techniques has profoundly modified the transfusion strategy of some clinical teams.
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The skin has an inherent region-specific anatomical diversity that may profoundly modify the appearance of a rash.
Nor does it seem possible that each of these would not under all circumstances profoundly modify the others, in keeping with learning and with inherited and other qualities specific to any particular brain.
The issue explained looks at the fundamental principles of best value, and examines why the government has decided to profoundly modify the policy by creating a new set of local government performance league tables and introducing new full council inspections.
These findings enable the rational design of therapeutic strategies which it is hoped will profoundly modify the progression of these diseases.
As a result of these trophic interactions, and of nontrophic ones such as mutualisms or ecosystem engineering, invasions can profoundly modify the structure of the entire food web.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com