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It is profoundly insoluble and consists of heme units dimerized through reciprocal iron-carboxylate bonds [24].
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This is demonstrated by the accumulation of SUMO-2 protein in a HMW insoluble fraction from human HD striatum, the region most profoundly affected in HD.
Profoundly Loved, Profoundly Missed.
The solutions are insoluble.
Profoundly missed.
Profoundly grateful.
The dilemma is perhaps insoluble.
It may be an insoluble problem.
He must be as insoluble as Iago.
But surely not an insoluble one.
No international dilemma is per se insoluble.
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