When Patagonia – led by visionary CEO Rose Marcario, who believes "we live in an interconnected world" that our actions affect "profoundly" – identifies aspects of their supply chain that aren't aligned with their organizational values, they do their best to fix the problem instead of simply moving on to another vendor.
None of these, sadly, is either Marlowe or Shakespeare, or even Harold Bloom, but their example demonstrates, I think, that the disputatious professor identified something profoundly important for our understanding - such as it is - of creativity and its mysteries.
Within decades of his death in 1201/02, prophecies attributed to him circulated that were identified (in profoundly un-Augustinian fashion) with current events: Franciscans and Dominicans, Holy Roman emperors, and popes all figured in grand, ever-shifting predictions of imminent apocalypse.
Using IPA, several profoundly affected pathways were identified.
"Because of successful identity politics, people have come to identify profoundly with other kinds of groups — 'I am a Jew,' or 'a French person.' But it's not likely with 'I am an ugly person and let's have a meeting of all ugly people.' Most people in general would want to disclaim membership.
Whenever I make the sign of the cross, I am profoundly conscious of identifying with Jesus Christ and standing in the flow of Christians from different backgrounds and traditions who have tenaciously and courageously confronted the idolatry and the evil of their times under the shadow of the cross.
Yet dense writing did not stop orientalism from achieving a wide international readership – nor did shaky history unsettle what Plumb identified as the "profoundly interesting concept" at the book's heart, that western attitudes about "the orient" have been produced and prejudiced by imperial power.
Nicholas Serota, the director of the Tate, said in a statement that Mr. Turnbull's art had come from his "admiration for the simple forms of ancient and Eastern cultures and his abiding search for the essence in any object," but that it "always had a humanist sensibility that identified it as profoundly European".
To date, different pathogenic mechanisms have been identified that can profoundly impact the epigenetic derangements in rheumatoid arthritis synovial fibroblasts, including increased consumption of S-adenosylmethionine, a principal methyl donor in DNA methylation reactions, together with deregulation of crucial DNA -and histone-modifying enzymes.
miR-217 was identified as the most profoundly regulated miRNAs in senescent human umbilical endothelial cells (Menghini et al, 2009).
