Sentence examples for profoundly essential from inspiring English sources

Sherly Sandberg evidently believes that Netflix's humble management document reveals something profoundly essential to its philosophy.

ICTJ's experience has shown, in every conceivable context, that the active participation of women is an essential and profoundly important element for the success of a truth commission and other transitional justice measures.

The supposed role of CR1 in CSCs seems corroborated by the observation that CR1 silencing profoundly affects signaling pathways essential for CSC growth.

Blocking KAP1 recruitment via mutagenesis would require the fine mapping of KAP1 recruiting site and their deletion or mutation, which for close to 30 such sites detected on the HCMV genome is not only daunting but unlikely to be possible without profoundly perturbing other features essential to the virus.

"The Pledge," like "Humanite," is a profoundly gloomy meditation on the essential bestiality of human (especially the male human) condition.

Auditory brainstem response (ABR) analysis demonstrated that mice homozygous for the missense mutation are profoundly deaf, consistent with an essential role for otoferlin in inner hair cell neurotransmission.

Instead, we discovered that slower decoding via hypomodified tRNAs elicits the aggregation of many essential proteins and profoundly impairs the ability of cells to balance protein homeostasis during stress.

In their study, Wu et al. show that impairment of autophagy, via deletion of the Atg7 gene that is essential for the process, profoundly influences mitochondrial function.