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There can be no doubt that for many communities these past two weeks have been profoundly damaging.
As it gradually became clear that the underlying illness was neither pneumonia nor cancer but a sexually transmitted disease that was profoundly damaging the immune system, experts argued their many theories about the cause.
The American war in Indochina, profoundly damaging on the other side of Thai borders, ushered Thailand into a profitable peace, as a whole industry of indulgence blossomed to cater to weary warriors.
I think it would be profoundly damaging to our economy.
But the consequences could be profoundly damaging for all involved.
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Part of the appeal of the story lies in its revelation of a profoundly damaged man.
Eliminating federal funding would profoundly damage public broadcasting as a whole.
But in both areas scalloping has profoundly damaged the ocean's delicate ecosystem.
"T-Mobile is probably going to be profoundly damaged by this," Tero Kuittinen, an independent research analyst, said.
This unprecedented event would profoundly damage the government's credit rating and send the financial system into a tailspin.
For the most part, these are alienated and dysfunctional people, some profoundly damaged by childhood neglect or abuse.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com